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  • LATEST MANUSCRIPTS IN Acta Pharmaceutica Sinica B
  • Yanping Wang, Weihong Du, Xiaoyan Hu, Xin Yu, Chun Guo, Xinchun Jin, Wei Wang. Targeting the blood-brain barrier to delay aging-accompanied neurological diseases by modulating gut microbiota, circadian rhythms, and their interplays. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4667-4687
    Cited : 12
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  • Jing Ye, Jin Zhang, Yanghui Zhu, Lian Wang, Xian Jiang, Bo Liu, Gu He. Targeting autophagy and beyond: Deconvoluting the complexity of Beclin-1 from biological function to cancer therapy. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4688-4714
    Cited : 7
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  • Chuanfeng Liu, Lide Hu, Guanyu Dong, Ying Zhang, Edeildo Ferreira da Silva-Júnior, Xinyong Liu, Luis Menéndez-Arias, Peng Zhan. Emerging drug design strategies in anti-influenza drug discovery. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4715-4732
    Cited : 5
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  • Mingjin Wang, Weida Wang, Shen You, Zhenyan Hou, Ming Ji, Nina Xue, Tingting Du, Xiaoguang Chen, Jing Jin. ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4733-4747
    Cited : 2
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  • Yingqiang Liu, Zhengsheng Zhan, Zhuang Kang, Mengyuan Li, Yongcong Lv, Shenglan Li, Linjiang Tong, Fang Feng, Yan Li, Mengge Zhang, Yaping Xue, Yi Chen, Tao Zhang, Peiran Song, Yi Su, Yanyan Shen, Yiming Sun, Xinying Yang, Yi Chen, Shanyan Yao, Hanyu Yang, Caixia Wang, Meiyu Geng, Wenbin Li, Wenhu Duan, Hua Xie, Jian Ding. Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4748-4764
    Cited : 5
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  • Xuesong Li, Xiang Chen, Longbin Zheng, Minghong Chen, Yunjia Zhang, Ruigong Zhu, Jiajing Chen, Jiaming Gu, Quanwen Yin, Hong Jiang, Xuan Wu, Xian Ji, Xin Tang, Mengdie Dong, Qingguo Li, Yuanqing Gao, Hongshan Chen. Non-canonical STING-PERK pathway dependent epigenetic regulation of vascular endothelial dysfunction integrating IRF3 and NF-B in inflammatory response. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4765-4784
    Cited : 7
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  • Shixin Duan, Xinyi Lou, Shiyi Chen, Hongchao Jiang, Dongxin Chen, Rui Yin, Mengkai Li, Yuseng Gou, Wenjuan Zhao, Lei Sun, Feng Qian. Macrophage LMO7 deficiency facilitates inflammatory injury metabolic-epigenetic reprogramming. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4785-4800
    Cited : 5
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  • Kaikai Zhang, Lijian Chen, Jianzheng Yang, Jiali Liu, Jiahao Li, Yi Liu, Xiuwen Li, Long Chen, Clare Hsu, Jiahao Zeng, Xiaoli Xie, Qi Wang. Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression- and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4801-4822
    Cited : 15
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  • Wenjun Yu, Haixia Xu, Zhe Sun, Yuxin Du, Shiqun Sun, Miyesaier Abudureyimu, Mengjiao Zhang, Jun Tao, Junbo Ge, Jun Ren, Yingmei Zhang. TBC1D15 deficiency protects against doxorubicin cardiotoxicity inhibiting DNA-PKcs cytosolic retention and DNA damage. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4823-4839
    Cited : 4
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  • Junting Zhang, Yiying Li, Jianchao Zhang, Lu Liu, Yuan Chen, Xusheng Yang, Xueyi Liao, Muhua He, Zihui Jia, Jun Fan, Jin-Song Bian, Xiaowei Nie. ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through 1-methyladenosine modification of circCDK17. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4840-4855
    Cited : 6
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  • Yong Ke, En Zhang, Jianming Guo, Xiaoxiao Zhang, Lei Wang, Duo Chen, Xinkui Fang, Jianwei Zhu, Feng Li, Tao Sun, Baohong Zhang. Immunogenicity of mucosal COVID-19 vaccine candidates based on the highly attenuated vesicular stomatitis virus vector (VSV) in golden syrian hamster. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4856-4874
    Cited : 1
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  • Wenjing Yu, Yuehuai Hu, Zhiping Liu, Kaiteng Guo, Dinghu Ma, Mingxia Peng, Yuemei Wang, Jing Zhang, Xiaolei Zhang, Panxia Wang, Jiguo Zhang, Peiqing Liu, Jing Lu. Sorting nexin 3 exacerbates doxorubicin-induced cardiomyopathy regulation of TFRC-dependent ferroptosis. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4875-4892
    Cited : 8
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  • Youchao Deng, Xiaosheng Song, Iredia D Iyamu, Aiping Dong, Jinrong Min, Rong Huang. A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4893-4905
    Cited : 2
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  • Li-Min Zhao, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen. Structure-based design of novel heterocycle-substituted ATDP analogs as non-nucleoside reverse transcriptase inhibitors with improved selectivity and solubility. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4906-4917
    Cited : 4
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  • Feifei Fang, Yang Dai, Hao Wang, Yinchun Ji, Xuewu Liang, Xia Peng, Jiyuan Li, Yangrong Zhao, Chunpu Li, Danyi Wang, Yazhou Li, Dong Zhang, Dan Zhang, Meiyu Geng, Hong Liu, Jing Ai, Yu Zhou. Structure-based drug discovery of novel fused-pyrazolone carboxamide derivatives as potent and selective AXL inhibitors. Acta pharmaceutica Sinica. B. 2023, 13 (12): 4918-4933
    Cited : 4
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