SUBJECTS : Trial Methodology | Trial Protocols | Randomised Controlled Trials | Medical Trial
Trials: 2023, vol: 24, issue: 1
- 1)- S B Patil, M Tamirat, K Khazhidinov, E Ardizzoni, M Atger, A Austin, E Baudin, M Bekhit, S Bektasov, E Berikova, M Bonnet, R Caboclo, M Chaudhry, V Chavan, S Cloez, J Coit, S Coutisson, Z Dakenova, B C De Jong, C Delifer, S Demaisons, J M Do, D Dos Santos Tozzi, V Ducher, G Ferlazzo, M Gouillou, U Khan, M Kunda, N Lachenal, A N LaHood, L Lecca, M Mazmanian, H McIlleron, M Moreau, M Moschioni, P Nahid, E Osso, L Oyewusi, S Panda, A Pâquet, P Thuong Huu, L Pichon, M L Rich, P Rupasinghe, N Salahud. Evaluating newly approved drugs in combination regimens for multidrug-resistant tuberculosis with fluoroquinolone resistance (endTB-Q): study protocol for a multi-country randomized controlled trial. Trials. 2023, 24 (1): 773
Cited : 0Read More - 2)- T Dixon, K S Cadenhead. Cannabidiol versus placebo as adjunctive treatment in early psychosis: study protocol for randomized controlled trial. Trials. 2023, 24 (1): 775Cited : 1Read More
- 3)- Jesse Ross, Rubeshan Perumal, Allison Wolf, Mbali Zulu, Kevin Guzman, Boitumelo Seepamore, Karl Reis, Hlengiwe Nyilana, Senzo Hlathi, Radhamoney Narasimmulu, Ying Kuen K Cheung, K Rivet Amico, Gerald Friedland, Amrita Daftary, Jennifer R Zelnick, Kogieleum Naidoo, Max R O'Donnell. Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South Africa (ADAP-TIV): study protocol for an adaptive randomized controlled trial. Trials. 2023, 24 (1): 776Cited : 1Read More
- 4)- A Juszczyk-Kalina, P Holas, T J Farchione. Effectiveness and mediators of change of an online CBT intervention for students with adjustment disorder-study protocol for a randomized controlled trial. Trials. 2023, 24 (1): 777Cited : 0Read More
- 5)- Dongke Wang, Dan Zhou, Xinghuang Liu, Zhiyue Xu, Tao Bai, Xiaohua Hou. Different dosages of vonoprazan for gastroesophageal reflux disease: study protocol for a pragmatic, crossover-cluster, randomized controlled trial with patient preference arms. Trials. 2023, 24 (1): 778Cited : 0Read More
- 6)- Sam Crosby, Adriana Malavisi, Liping Huang, Stephen Jan, Richard Holden, Bruce Neal. Factors influencing the time to ethics and governance approvals for clinical trials: a retrospective cross-sectional survey. Trials. 2023, 24 (1): 779Cited : 0Read More
- 7)- Eduardo F Marins, Eduardo L Caputo, Vitor L Krüger, Dirceu M Junior, Fabrício G Scaglioni, Fabricio B Del Vecchio, Tiago T Primo, Cristine L Alberton. Effectiveness of m-health-based core strengthening exercise and health education for public safety workers with chronic non-specific low back pain: study protocol for a superiority randomized controlled trial (SAFEBACK). Trials. 2023, 24 (1): 780Cited : 0Read More
- 8)- Wei Peng, Mengshi Yi, Xin Qi, Weili Qi, Chuan Li, Tianfu Wen. The effect of switch therapy to tenofovir versus entecavir maintenance on recurrence of hepatocellular carcinoma after surgery (SWITE): study protocol for a randomized controlled trial. Trials. 2023, 24 (1): 781Cited : 0Read More
- 9)- Amy Brenner, Haleema Shakur-Still, Rizwana Chaudhri, Projestine Muganyizi, Oladapo Olayemi, Monica Arribas, Aasia Kayani, Kiran Javid, Adenike Bello, Ian Roberts, . Tranexamic acid by the intramuscular or intravenous route for the prevention of postpartum haemorrhage in women at increased risk: a randomised placebo-controlled trial (I'M WOMAN). Trials. 2023, 24 (1): 782Cited : 0Read More
- 10)- Xavier Corominas-Teruel, Martina Bracco, Montserrat Fibla, Rosa Maria San Segundo, Marc Villalobos-Llaó, Cecile Gallea, Benoit Beranger, Monica Toba, Antoni Valero-Cabré, Maria Teresa Colomina. High-density transcranial direct current stimulation to improve upper limb motor function following stroke: study protocol for a double-blind randomized clinical trial targeting prefrontal and/or cerebellar cognitive contributions to voluntary motion. Trials. 2023, 24 (1): 783Cited : 0Read More
- 11)- Ellen Murphy, Katie Gillies, Frances Shiely. How do trial teams plan for retention during the design stage of the trial? A scoping review. Trials. 2023, 24 (1): 784Cited : 1Read More
- 12)- B Wertheim, E E Aarts, C de Roos, Y R van Rood. The effect of eye movement desensitization and reprocessing (EMDR) on abdominal pain in patients with irritable bowel syndrome (IBS): a study protocol for a randomized controlled trial (EMDR4IBS). Trials. 2023, 24 (1): 785Cited : 0Read More
- 13)- Rui Qi Gao, Zhen Chang Mo, Hai Kun Zhou, Peng Fei Yu, Wei Dong Wang, Dan Hong Dong, Xi Sheng Yang, Xiao Hua Li, Gang Ji. A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer. Trials. 2023, 24 (1): 786Cited : 0Read More
- 14)- Nian-Rong Han, Akram Osman, Wei Hu, Yi-Fei Huang, Yan-Lu Liu, Zhan-Jun Ma. Effect of spinal orthosis on clinical outcomes of patients after oblique lumbar interbody fusion: a randomized controlled trial study protocol. Trials. 2023, 24 (1): 787Cited : 0Read More
- 15)- Qiurong Xie, Jinsong Wu, Qi Zhang, Yanxin Zhang, Bo Sheng, Xiaoling Wang, Jia Huang. Neurobiomechanical mechanism of Tai Chi to improve upper limb coordination function in post-stroke patients: a study protocol for a randomized controlled trial. Trials. 2023, 24 (1): 788Cited : 1Read More
- 16)- Cong-Xian Wu, Cheng-Hsin Li, Yi-Hsien Shiao, Huan-Yu Cheng, Tsung-Han Wu, Chun-Hui Lee, Zi-Yu Chang, Yuan-Chieh Yeh. The effect of a helmet type, home-use low-level light therapy device for chemotherapy-induced alopecia: study protocol for a randomized controlled trial. Trials. 2023, 24 (1): 789Cited : 0Read More
- 17)- Qing Xu, Tiana J McMann, Jiawei Li, Christine Wenzel, Tim K Mackey. Characterization of COVID-19 vaccine clinical trial discussions on the social question-and-answer site Quora. Trials. 2023, 24 (1): 790Cited : 0Read More
- 18)- Jojo Yan Yan Kwok, Daphne Sze Ki Cheung, Steven Zarit, Karen Siu-Lan Cheung, Bobo Hi Po Lau, Vivian Weiqun Lou, Sheung-Tak Cheng, Dolores Gallagher-Thompson, Kee-Lee Chou. Multiphase optimization of a multicomponent intervention for informal dementia caregivers: a study protocol. Trials. 2023, 24 (1): 791Cited : 0Read More
- 19)- Flavia L Lombardo, Stefania Spila Alegiani, Flavia Mayer, Marta Cipriani, Maria Lo Giudice, Albert Christian Ludolph, Christopher J McDermott, Philippe Corcia, Philip Van Damme, Leonard H Van den Berg, Orla Hardiman, Gabriele Nicolini, Nicola Vanacore, Brian Dickie, Alberto Albanese, Maria Puopolo, . A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial. Trials. 2023, 24 (1): 792Cited : 1Read More
- 20)- Kate Walters, Megan Armstrong, Benjamin Gardner, Gareth Ambler, Rachael Hunter, Bev Maydon, Nathan Davies, Catherine Atkinson, Richard Brown, Tasmin Rookes, Daniel Davis, Anette Schrag. Clinical and cost-effectiveness of 'Live Well with Parkinson's' self-management intervention versus treatment as usual for improving quality of life for people with Parkinson's: study protocol for a randomised controlled trial. Trials. 2023, 24 (1): 793Cited : 0Read More
- 21)- Emma Kwan-Yee Ho, Ralph Jasper Mobbs, James Montague van Gelder, Ian Andrew Harris, Gavin Davis, Ralph Stanford, David John Beard, Christopher Gerard Maher, Joanna Prior, Michael Knox, David Barrett Anderson, Rachelle Buchbinder, Manuela Loureiro Ferreira. Challenges of conducting a randomised placebo-controlled trial of spinal surgery: the SUcceSS trial of lumbar spine decompression. Trials. 2023, 24 (1): 794Cited : 0Read More
- 22)- Robert K Mahar, Anna McGlothlin, Michael Dymock, Todd C Lee, Roger J Lewis, Thomas Lumley, Jocelyn Mora, David J Price, Benjamin R Saville, Tom Snelling, Rebecca Turner, Steven A Webb, Joshua S Davis, Steven Y C Tong, Julie A Marsh, . A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial. Trials. 2023, 24 (1): 795Cited : 2Read More
- 23)- Diane Heels-Ansdell, Laurent Billot, Lehana Thabane, Waleed Alhazzani, Adam Deane, Gordon Guyatt, Simon Finfer, François Lauzier, John Myburgh, Paul Young, Yaseen Arabi, John Marshall, Shane English, John Muscedere, Marlies Ostermann, Bala Venkatesh, Nicole Zytaruk, Miranda Hardie, Naomi Hammond, Serena Knowles, Lois Saunders, Alexis Poole, Abdulrahman Al-Fares, Feng Xie, Richard Hall, Deborah Cook. REVISE: re-evaluating the inhibition of stress erosions in the ICU-statistical analysis plan for a randomized trial. Trials. 2023, 24 (1): 796Cited : 2Read More
- 24)- Alejandro Rodríguez-Molinero, Gerard Carot-Sans, Roser Escrig, Cristian Tebé, Jacobo Arce, Carlos Pérez-López, Silvia Ballesta, Guillermo Verdejo, Ángel Cedeño, Mar Riera-Pagespetit, Sofia Vivas-Angeles, Jose L Alarcon, Itziar Navarro, Silvia Toro, Llorenç Mateo, Ana J Torres, Gerard Delmás, Helena Camell, Antonio Chamero, Montse Gasol, Jordi Piera-Jiménez, . Study protocol of a randomized controlled trial to assess safety of teleconsultation compared with face-to-face consultation: the ECASeT study. Trials. 2023, 24 (1): 797Cited : 1Read More
- 25)- Adrian Krotz, Nadia Sosnowsky-Waschek, Stephanie Bechtel, Christine Neumann, Monika Lohkamp, Gabor Kovacs, Bernd Genser, Joachim E Fischer. Reducing sick leave, improving work ability, and quality of life in patients with mild to moderate Long COVID through psychosocial, physiotherapeutic, and nutritive supportive digital intervention (MiLoCoDaS): study protocol for a randomized controlled trial. Trials. 2023, 24 (1): 798Cited : 0Read More
- 26)- Edward L Snyder, Michael E Sekela, Ian J Welsby, Yoshiya Toyoda, Mohamed Alsammak, Neel R Sodha, Thomas M Beaver, J Peter R Pelletier, James D Gorham, John S McNeil, Roman M Sniecinski, Ronald G Pearl, Gregory A Nuttall, Ravi Sarode, T Brett Reece, Alesia Kaplan, Robertson D Davenport, Tina S Ipe, Peyman Benharash, Ileana Lopez-Plaza, Richard R Gammon, Patrick Sadler, John P Pitman, Kathy Liu, Stanley Bentow, Laurence Corash, Nina Mufti, Jeanne Varrone, Richard J Benjamin, . Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) study-protocol for a phase 3, randomized, controlled trial. Trials. 2023, 24 (1): 799Cited : 1Read More
- 27)- Rens W J Kooken, Bram Tilburgs, Rob Ter Heine, Bart Ramakers, Mark van den Boogaard, . A multicomponent intervention program to Prevent and Reduce AgItation and phySical rEstraint use in the ICU (PRAISE): study protocol for a multicenter, stepped-wedge, cluster randomized controlled trial. Trials. 2023, 24 (1): 800Cited : 0Read More
- 28)- Tove Godskesen, Joar Björk, Niklas Juth. Challenges regarding informed consent in recruitment to clinical research: a qualitative study of clinical research nurses' experiences. Trials. 2023, 24 (1): 801Cited : 1Read More
- 29)- Lena Morgon Banks, Stella Kepha, Anja Zinke-Allmang, Paul M Gichuki, Nathaniel Scherer, Charles Mwandawiro, Mark Carew, Doris Njomo, Shanquan Chen, Collins Okoyo, Calum Davey, Tom Shakespeare, Maria Antonella Pereira, Divya Goyal, Hannah Kuper. Impact of a disability-targeted microentrepreneurship programme in Kenya: study protocol for a randomised controlled trial of the InBusiness programme. Trials. 2023, 24 (1): 802Cited : 0Read More
- 30)- Jiayan Chen, Yimeng Chen, Guanghao Qin, Liangzhe Li, Mingze Li, Yuan Cheng, Shuting Zhuang, Zhihui Li, Qing Zhang, Yi Wu, Lanting Yang, Salissou Moutari, Jonathan E Moore, Ling Xu, Wei He, Sile Yu, Emmanuel Eric Pazo, Xingru He. A protocol for a single center, randomized, controlled trial comparing the clinical efficacy of 3% diquafosol and 0.1% hyaluronic acid in diabetic patients with dry eye disease. Trials. 2023, 24 (1): 803Cited : 0Read More
- 31)- Laura F Salazar, Dominic J Parrott, David DiLillo, Sarah Gervais, Anne Marie Schipani-McLaughlin, Ruschelle Leone, Kevin Swartout, Lauren Simpson, Renita Moore, Tiffany Wilson, Nyla Flowers, Haley Church, Amanda Baildon. Study protocol for a randomized controlled trial of RealConsent2.0: a web-based intervention to promote prosocial alcohol-involved bystander behavior in young men. Trials. 2023, 24 (1): 804Cited : 0Read More
- 32)- Shenglin Xu, Junfen Wang, Jianian Guo, Fang Xie, Weiguang Qiao, Yiteng Meng, Peng Peng, Haiyan Hu, Ying Huang, Side Liu, Mengbin Qin, Jun Yao, Yue Li. Dry suction versus wet suction technique of endoscopic ultrasound-guided fine-needle biopsy for diagnosis of solid pancreatic lesions: study protocol of a multicenter randomized controlled non-inferiority trial. Trials. 2023, 24 (1): 805Cited : 0Read More
- 33)- Jamlick Karumbi, David Gathara, Bridget Young, Paula Williamson. To adopt or adapt an existing neonatal core outcome set in Kenya: a study protocol. Trials. 2023, 24 (1): 806Cited : 0Read More
- 34)- I A El Karim, H F Duncan, A F Fouad, N A Taha, V Yu, S Saber, V Ballal, P Chompu-Inwai, H M A Ahmed, B P F A Gomes, S Abushouk, S Cushley, C O'Neill, M Clarke. Effectiveness of full Pulpotomy compared with Root canal treatment in managing teeth with signs and symptOms indicative of irreversible pulpitis: a protocol for prospectiVE meta-analysis of individual participant data of linked randomised clinical trials (PROVE). Trials. 2023, 24 (1): 807Cited : 2Read More
- 35)- Jasmine Melissa Madsen, Laust Emil Roelsgaard Obling, Laura Rytoft, Fredrik Folke, Christian Hassager, Lars Bredevang Andersen, Niels Vejlstrup, Lia Evi Bang, Thomas Engstrøm, Jacob Thomsen Lønborg. Pre-hospital pulse glucocorticoid therapy in patients with ST-segment elevation myocardial infarction transferred for primary percutaneous coronary intervention: a randomized controlled trial (PULSE-MI). Trials. 2023, 24 (1): 808Cited : 0Read More
- 36)- Emerson Lee, Jonathan Coulter, Alok Mishra, Fernanda Caramella-Pereira, Angelo Demarzo, Michelle Rudek, Chen Hu, Misop Han, Theodore L DeWeese, Srinivasan Yegnasubramanian, Daniel Y Song. Induction of double-strand breaks with the non-steroidal androgen receptor ligand flutamide in patients on androgen suppression: a study protocol for a randomized, double-blind prospective trial. Trials. 2023, 24 (1): 809Cited : 0Read More
- 37)- Carolina Hawranek, Hans Ehrencrona, Anna Öfverholm, Barbro Numan Hellquist, Anna Rosén. Direct letters to relatives at risk of hereditary cancer-study protocol for a multi-center randomized controlled trial of healthcare-assisted versus family-mediated risk disclosure at Swedish cancer genetics clinics (DIRECT-study). Trials. 2023, 24 (1): 810Cited : 2Read More
- 38)- Xue Yu, Lejia Xu, Jiaxing Zheng, Ziying Lei, Yihua Pang, Xiaojie Li, Jianyun Zhu, Jing Liu. Efficacy and safety of voriconazole in the treatment of invasive pulmonary aspergillosis in patients with liver failure: study protocol for a randomized controlled clinical trial. Trials. 2023, 24 (1): 811Cited : 0Read More
- 39)- Yilin Wang, Yu Jiang, Jia Li, Xisheng Lin, Yan Luo, Shuhuai Tan, Haohan Yang, Zefu Gao, Xiang Cui, Pengbin Yin, Dan Kong, Yuan Gao, Yu Cheng, Licheng Zhang, Peifu Tang, Houchen Lyu. Effect of denosumab on glucose metabolism in postmenopausal osteoporotic women with prediabetes: a study protocol for a 12-month multicenter, open-label, randomized controlled trial. Trials. 2023, 24 (1): 812Cited : 0Read More
- 40)- Eva Tolmeijer, Felicity Waite, Louise Isham, Laura Bringmann, Robin Timmers, Arjan van den Berg, Hanneke Schuurmans, Anton B P Staring, Paul de Bont, Rob van Grunsven, Gert Stulp, Ben Wijnen, Mark van der Gaag, Daniel Freeman, David van den Berg. Correction: Testing the combination of Feeling Safe and peer counselling against formulation-based cognitive behaviour therapy to promote psychological wellbeing in people with persecutory delusions: study protocol for a randomized controlled trial (the Feeling Safe-NL Trial). Trials. 2023, 24 (1): 813Cited : 0Read More
- 41)- Giovanfrancesco Ferrari, Samuel Makali Lwamushi, Ghislain Bisimwa Balaluka, Riyadh K Lafta, Christian Schindler, Daniella Bugugu, Emmanuel Lurhangire, Fabrizio Tediosi, Jessica Ramirez Mendoza, Sonja Merten. Understanding context of violence against healthcare through citizen science and evaluating the effectiveness of a co-designed code of conduct and of a tailored de-escalation of violence training in Eastern Democratic Republic of Congo and Iraq: a study protocol for a stepped wedge randomized controlled trial. Trials. 2023, 24 (1): 814Cited : 0Read More
- 42)- Josephine Bourner, Ravaka Randriamparany, Tsinjo Fehizoro Rasoanaivo, Emmanuelle Denis, Rindra Vatosoa Randremanana, Michel Vaillant, Alex Paddy Salam, Bronner P Gonçalves, Piero Olliaro. Bubonic plague: can the size of buboes be accurately and consistently measured with a digital calliper? Trials. 2023, 24 (1): 815Cited : 0Read More
- 43)- Qin Tan, Lu Zhou, Yihan Lu, Weifeng Huang. Comparison of different intervention methods to reduce the incidence of venous thromboembolism: study protocol for a cluster-randomized, crossover trial. Trials. 2023, 24 (1): 816Cited : 0Read More
- 44)- Chen Chen, Yapeng Lin, Feifeng Liu, Xiaoying Chen, Laurent Billot, Qiang Li, Yiija Guo, Hueiming Liu, Lei Si, Menglu Ouyang, Chunfang Zhang, Hisatomi Arima, Philip M Bath, Gary A Ford, Thompson Robinson, Else Charlotte Sandset, Jeffrey L Saver, Nikola Sprigg, H Bart van der Worp, Gang Liu, Lili Song, Jie Yang, Gang Li, Craig S Anderson, . Update on the INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): progress and baseline features in 2053 participants. Trials. 2023, 24 (1): 817Cited : 2Read More
- 45)- Richard J Derman, Roopa B Bellad, Mrutyunjaya B Bellad, Jesse Bradford-Rogers, Michael K Georgieff, Zubair H Aghai, Simal Thind, Michael Auerbach, Rupsa Boelig, Benjamin E Leiby, Vanessa Short, S Yogeshkumar, Umesh S Charantimath, Manjunath S Somannavar, Ashalata A Mallapur, Ramesh Pol, Umesh Ramadurg, Radha Sangavi, Basavaraj V Peerapur, Nasima Banu, Praveen S Patil, Amaresh P Patil, Subarna Roy, Phaniraj Vastrad, Dennis Wallace, Hemang Shah, Shivaprasad S Goudar. RAPIDIRON Trial follow-up study - the RAPIDIRON-KIDS Study: protocol of a prospective observational follow-up study. Trials. 2023, 24 (1): 818Cited : 0Read More
- 46)- Xiang Yan, Chen Liang, Jia Jiang, Ying Ji, Anshi Wu, Changwei Wei. Effects of opioid-free anaesthesia on postoperative nausea and vomiting in patients undergoing video-assisted thoracoscopic surgery (OFA-PONV trial): study protocol for a randomised controlled trial. Trials. 2023, 24 (1): 819Cited : 0Read More
- 47)- Mélanie Hébert, Serge Bourgault, Mathieu Caissie, Éric Tourville, Ali Dirani. REtinal Detachment Outcomes Study (REDOS): study protocol for a factorial, randomized controlled trial. Trials. 2023, 24 (1): 820Cited : 1Read More
- 48)- Huixi Chen, Yaoyao Tu, Chen Zhang, Jie Li, Ting Wu, Suying Liu, Liying He, Aijun Zhang, Yan Li, Lu Li, Yilun Sui, Li Wang, Xiaojun Chen, Ji Xi, Yanting Wu, Li Jin, He-Feng Huang. Effect of transvaginal Lactobacillus supplementation on reversing lower genital tract dysbiosis and improving perinatal outcomes in PCOS patients after IVF-FET: a study protocol for a multicenter randomized controlled trial. Trials. 2023, 24 (1): 821Cited : 0Read More
- 49)- Yosuke Nakadate, Mariko Yamada, Natsuyo Kusuyama, Ryota Ishii, Hiroaki Sato, Thomas Schricker, Makoto Tanaka. Effect of intranasal insulin administration on postoperative delirium prevention in elderly cardiac surgery patients: study protocol for a multicenter, double-blind, randomized, controlled trial. Trials. 2023, 24 (1): 822Cited : 0Read More
- 50)- Alex Martino Cinnera, Sonia Bonnì, Alessia D'Acunto, Michele Maiella, Matteo Ferraresi, Elias Paolo Casula, Valentina Pezzopane, Marco Tramontano, Marco Iosa, Stefano Paolucci, Giovanni Morone, Giuseppe Vannozzi, Giacomo Koch. Cortico-cortical stimulation and robot-assisted therapy (CCS and RAT) for upper limb recovery after stroke: study protocol for a randomised controlled trial. Trials. 2023, 24 (1): 823Cited : 1Read More
